Cruise Launches New Website As A 'Thank You' To Fans & other

Thursday, 14 August 2008

FDA Allows Phase 2 Study For Sound Pharmaceuticals' Novel Drug To Prevent Chemotherapy Induced Hearing Loss

�Sound Pharmaceuticals (SPI) has
received FDA notification that it whitethorn proceed with its Phase II survey to
forbid chemotherapy induced hearing red. The Ph-II study will enroll 80
patients with advanced nous and neck, and non-small cell lung cancer at the
National Center for Rehabilitative Auditory Research at the Veterans
Administration Hospital and the Oregon Health and Science University in
Portland, Oregon.

Hearing red due to ototoxic medications such as chemotherapy,
antibiotics or loop diuretics oft results in permanent and progressive
disablement. Furthermore, the combined habit of these ototoxic agents is
contraindicated, often limiting their clinical utility. Symptoms of
ototoxicity include hearing loss, tinnitus, dizziness, lightheadedness and
difficulty understanding speech. Historically, the incidence of cisplatin
or carboplatin-induced sense of hearing loss was widely under estimated or reported
due to unequal testing or a want of coverage. Recently, a new
behavioral audiometric protocol has been developed and employed to test an
individual's sensitive range for ototoxicity (SRO). This involves pure-tone
audiometry at very specific steps within a person's upper berth range of hearing.
With the SRO protocol, several studies right away report an incidence of
ototoxicity of 85-92% for cisplatin and carboplatin receiving cancer
patients, an incidence that is much greater than previously reported. One
of the goals of this Ph-II study is to shorten the incidence and severity of
the ototoxicity in platinum receiving cancer patients as measured by
pure tone audiometry victimisation the SRO protocol, distortion product otoacoustic
emissions (DPOAEs) and the tinnitus disablement inventory. DPOAEs are a
measure of outer hair cell single-valued function in the inner spike and ar another
sensitive and specific measure of ototoxicity.

In several preclinical studies, SPI has showed that its novel
chemoprotectant drug product, a humble molecule that mimics and induces
Glutathione Peroxidase activity was vital in preventing ototoxicity
patch not interfering with the chemotherapy treatment. In unmatchable rodent fashion model
of crab, the chemoprotectant enhanced the tumoricidal bodily process of
cisplatin.

Sound Pharmaceuticals, Inc.
http://www.soundpharma.com

More info

Wednesday, 6 August 2008

Kim Robertson and Singh Kaur

Artist: Kim Robertson and Singh Kaur

   Genre(s):
New Age

Discography:

Crimson Collection Vol. 6 and 7

Year: 1991
Tracks: 2

Crimson Collection Vol. 4 and 5

Year: 1991
Tracks: 3

Crimson Collection Vol. 1 and 2

Year: 1991
Tracks: 2

Friday, 27 June 2008

Nicola

Artist: Nicola

   Genre(s):
Folk: Moldavian and Romanian

Discography:

Compilatie

Year: 2002
Tracks: 1

First He Swept, Now Boy George Will Sing

Thursday, 19 June 2008

Juror asks to be removed from R. Kelly trial

Judge receives note after break in deliberations

CHICAGO -- Two jurors are having issues at R. Kelly's child pornography trial.
One sent a note to the judge after three hours of deliberations Friday that reads: "How can I be removed and go home? I really need to."
Judge Vincent Gaughan called attorneys into the courtroom, told them about the note but adjourned before dealing with the matter. The jury had stopped deliberating for lunch.
Earlier in the morning, the judge called attorneys in to discuss another juror, who became frustrated by slow service during dinner the night before and started banging a bottle on the table and cursing. That juror was allowed to remain on the panel after other jurors indicated they could continue working with him.

Saturday, 14 June 2008

Dizzee Rascal Sets Second US Tour This Year

UK rapper Dizzee Rascal has just finished off a US tour last week and already he's planning his return for later in the Summer.

After some UK festivals this month and next, Dizzee will jet off to the States again in mid-July, to play seven shows.

These shows, as with the recent jaunt, see Rascal promoting the long overdue US release of his third album 'Maths + English' - out now on Def Jux.

July Dates:

18th - New York, NY, Highline Ballroom

19th - Chicago, IL, Pitchfork

20th - Toronto, ON, Rogers Picnic

21st - Austin, TX, Emo's

22nd - Denver, CO, Cervante's

J24th - Los Angeles, CA, Echoplex

25th - San Francisco, CA, Mezzanine

See Also